Silver-Catalyzed Radical Ring-Opening Reaction of Cyclopropanols with Sulfonyl Oxime Ethers. 0000005376 00000 n reduction of oximes to primary amines6,7 by above method has been found to be an efficient and best method for the large-scale synthesis of primary amines.
0000003454 00000 n 112 0 obj <> endobj H��WK�%� ]A�ACg�j�?C��C�~@IF��/A;o?��(Q�F��@�wX�! 0000091228 00000 n %%EOF 0000004402 00000 n 0000001758 00000 n <<53D0C71F1C5C314991B31C3E41370734>]>> 0000004807 00000 n 0000003022 00000 n 0000027789 00000 n The literature review shows that sodium borohydride alone do not have the reactivity to reduce oximes under any conditions. �>:&�-JS�L�J�VG]M%_�S����������J�z��MͪeU�@o��CPP0���x �Eai0Ёl���� H#Bdtt �g666�T�"N i n��1�3:��`qt�o�< ����I�{G�v�á��:6F�M�4�0�0gpt��qk�ced�c6ѐ����hw�K��C�śvGU9r7�P�`~��kb�c�� ���D�ep9. �3qI�f/�1�����@�c�g���M���p�; 0000011644 00000 n Reduction to amines [LiAlH 4] Explained:. Its reactivi ty is similar to catalytic hydrogenation and is different from reducing profile of sodium borohydride … 0000002578 00000 n %PDF-1.2 %����
73 0 obj << /Linearized 1 /O 75 /H [ 1183 392 ] /L 444213 /E 45923 /N 10 /T 442635 >> endobj xref 73 39 0000000016 00000 n x�b```f``����� �� Ā B�,_&�2$����s�/P�]Ȍ���0`��PTp`cwa�pb�t ���sw� 0000002370 00000 n 0000006497 00000 n 0000001128 00000 n Reduction of oximes. E-mail address: b.zeynizadeh@mail.urmia.ac.ir. 0000001799 00000 n 0000001579 00000 n 0000012752 00000 n 0000019682 00000 n ChemInform Abstract: Reduction of Oximes with Sodium Borohydride—Copper(II) Sulfate in Methanol. 0000008964 00000 n Vogel's practical organic chemistry uses ethanol and sodium metal to reduce oximes to amines. Xiaobao Zeng, Xin Wang, Yanan Zhang, Li Zhu, Yu Zhao. �� �QU࣪KU���b�h�ì� A���9HZg1���|W3�e��w�jZAC8�k��+� Sodium cyanoborohydride is a milder and more selective reducing agent than sodium borohydride 1. %%EOF � The selective reduction of oximes with sodium borohydride (NaBH4) in the presence of nano Cu and charcoal was investigated. 0000077532 00000 n 0000010281 00000 n 0000022498 00000 n Sulfurated sodium borohydride can reduce oximes to the corresponding amine with yields depending on the steric requirement of the oxime. In the reduction of oximes with copper (II) sulfate / sodium borohydride, imines are possible intermediates. 0000004848 00000 n 0000045679 00000 n 0000017658 00000 n
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but i'm not sure how to do the reduction from oxime to amine. 0000002275 00000 n An expeditious and practical method for the reduction of various amides and lactams to amines in good to excellent yields is consisted of activation with Tf 2 O followed by reduction with sodium borohydride in THF at room temperature. %PDF-1.6 %���� *��A���(�3���*핛�ښ�[]P�'rT[!�~(���*C�K�{�� �!l Q Lڟsi��g�1��h)����dډ�&� trailer 0000005104 00000 n 0000016482 00000 n 178 0 obj <>stream
112 67 0000034542 00000 n 0000099972 00000 n ��v/(,����O��Ή͌KJHNIMK�W�TQ�Pu�̏�bf�cg� ��T袨������^Q����1#+bFR|�������������pd(���$g+;��hqIEyei}uSMsCcK[�Wn�w�5��>Nή~�`�a���� 0000028054 00000 n First Report for the Efficient Reduction of Oximes to Amines with Zinc Borohydride in the form of (Pyridine)(tetrahydroborato)zinc Complex. 0000002297 00000 n 0000087209 00000 n 0000009023 00000 n 0000003148 00000 n 0000026552 00000 n 0000010044 00000 n 0000101822 00000 n 0000005542 00000 n 0000033688 00000 n 0000018369 00000 n 0000009896 00000 n 0000010358 00000 n 0000028279 00000 n �@ת1����V�[�5c���SӶ�!�(5���$�\�Xp���P��! 0000000016 00000 n 0000017793 00000 n @V�#�Cd��v��h}��z?��э�bv *#�M�h{Z=�@����Ȁ�
0000102048 00000 n 0000002455 00000 n Chemical Reviews 1976, 76 (6) , 773-799. 0000046693 00000 n 0000013026 00000 n 0000001553 00000 n Sodium borohydride, also known as sodium tetrahydridoborate and sodium tetrahydroborate, is an inorganic compound with the formula Na BH 4.This white solid, usually encountered as a powder, is a reducing agent that finds application in chemistry, both in the laboratory and on an industrial scale.
Electroreduction of Nitroalkenes to Oximes and Amines; Reductions with Sodium Borohydride/Sulfur - NaBH 2 S 3 (PDF) Reductions with Alkyloxyaluminohydrides, Red-Al etc.
0000003736 00000 n 0000001499 00000 n 0000020123 00000 n DOI: 10.1021/jo070591c. 0000099778 00000 n 0000001575 00000 n 0000014275 00000 n 0000010830 00000 n U#�y�[$cM���%=(��~�+�u�`P1�-5.�D_��M�lf�3gP3v�2.HC����GU�x!��TA��ų�h���{xZ.�&�tl�d#oA���c���0Vj��! ��V�}�Yu�^8��K��t�I�Y�Q�%�O��d� �5�r����Lq�����H���\+/� Behzad Zeynizadeh. 0000020365 00000 n Sodium cyanoborohydride is especially suitable for reductive aminations. 0000054198 00000 n
0000019730 00000 n 0000003933 00000 n 0000091926 00000 n Intermediate hydroxylamine can be obtained predominantly under appropriate experimental conditions. 0000087744 00000 n
�L �F��l�����06��a{� Ȥ����Ż��q��0��3��+i.�ٌ�H1�e��vw����{d}F����) �SE endstream endobj 111 0 obj 276 endobj 75 0 obj << /Type /Page /Parent 72 0 R /Resources 76 0 R /Contents [ 80 0 R 82 0 R 84 0 R 87 0 R 89 0 R 91 0 R 103 0 R 105 0 R ] /MediaBox [ 0 0 595 842 ] /CropBox [ 0 0 595 842 ] /Rotate 0 /Thumb 47 0 R >> endobj 76 0 obj << /ProcSet [ /PDF /Text /ImageB ] /Font << /F18 77 0 R /F19 85 0 R /F20 78 0 R /F21 94 0 R /F22 92 0 R /F23 93 0 R /F24 97 0 R /F25 95 0 R >> /XObject << /Im1 106 0 R /Im2 107 0 R >> /ExtGState << /GS2 109 0 R >> >> endobj 77 0 obj << /Type /Font /Subtype /Type1 /Name /F18 /Encoding /MacRomanEncoding /BaseFont /Helvetica >> endobj 78 0 obj << /Type /Font /Subtype /Type1 /Name /F18 /Encoding /MacRomanEncoding /BaseFont /Times-Roman >> endobj 79 0 obj 2774 endobj 80 0 obj << /Filter /FlateDecode /Length 79 0 R >> stream 0000014253 00000 n 0000006078 00000 n 0000011332 00000 n A practical method has been developed for reduction of C-N double bond in oximes, imines, and hydrazones with sodium borohydride catalyzed by Raney Ni. 0000027673 00000 n 0000007504 00000 n DOI: 10.1021/cr60304a005. Reduction of imine leads to primary amines. 0000006655 00000 n xref Lithium aluminum hydride, LiAlH 4 [but NOT sodium borohydride, NaBH 4] can reduce nitriles to primary amines.. Further reaction of imine with primary amine result in intermediates, which on further transformation furnish secondary amines. 58 0 obj<>stream 0000018134 00000 n 0000008153 00000 n startxref �1>\C4�,��%��!v����8��o�䩏]�+_L�\EJm&D݁����=� ����(��y��S��:$ʷH��^U�`Ѐ#A" (. 0000009479 00000 n 0000016362 00000 n